Tautomers are constitutional isomers that interconvert into each other by an exchange reaction, most commonly a proton transfer. Such two isomers can for example be a ketone and an enol. Keto-enol tautomerism (KET) becomes possible when there are hydrogen atoms adjacent to a carbonyl group (these hydrogen atoms are called α hydrogens). This tautomerism is depicted in Scheme 1 and is also discussed…

Have you ever been curious as to why your pumpkin spice latte doesn't taste like pumpkins? Pumpkin spice is actually a mix of spices; such as, nutmeg, ginger, cloves, cinnamon, etc. In this blog, we focus our attention on cinnamon, where we obtain the 1H NMR spectrum using benchtop NMR. We then compare this with known molecules that comprise cinnamon such as, cinnamic acid and cinnamaldehyde. Read more.

In this blog we will explore how a variety of acquisition parameters can affect the FID and their direct consequence in the spectrum.

Cathinone is a natural alkaloid occurring in the khat plant known for its mild stimulating effects when chewing the leaves which is of cultural importance in East Africa and the Middle East… Read more on our NMR blog

Chirality has a huge impact on the chemistry of a molecule. Due to potentially different physiological effects, pharmaceutical compounds are often used as enantiomerically pure compounds. One enantiomer can act as a healing agent, the other might be toxic to humans. Crazy, right?

It is well known that signal dispersion decreases as the NMR field strength is reduced. For example, at 400 MHz, 1 ppm spans 400 Hz while at 60 MHz, 1 ppm spans 60 Hz.

NMR users can deal with spectrum evaluation in the daily work, but how is the spectrum information stored in the time domain (FID)? Read more.

In NMR, the net magnetization is detected in the xy plane, giving rise to the FID (Free Induction Decay). The process by which the magnetization in the xy plane decays away, over time, to its equilibrium value of zero, is known as T2 relaxation, transversal relaxation, relaxation on the xy plane, or spin-spin relaxation.

In this blog post we show a simple experiment that teaches student how common over the counter (OTC) medications can be qualified and quantified for their different active pharmaceutical ingredients (API) using qNMR spectroscopy.

Nuclear Magnetic Resonance spectroscopy is based on the idea that some nuclei can behave as little magnetic bars (I spin number ≠ 0). In the presence of a magnetic field (B0) the nuclear spins feel a small torque for or against the B0 axis, which results in a net magnetization along the B0 direction. Benchtop NMR 1-855-NMREADY (667-3239) toll-free in the US and Canada.