Pharmaceuticals and Biotechnology

100 MHz

• Nanalysis 100PRO – Multinuclear
  e.g., 1H/19F/13C, 1H/19F/31P, 
etc. 


• Nanalysis 100e – 1H/19F 


60 MHz

• Nanalysis 60PRO – Multinuclear

  e.g., 1H/19F/13C, 1H/19F/31P, 1H/19F/11B, etc.


• Nanalysis 60e – 1H/19F


In addition to qualitative analysis, the quantitative nature of NMR can address a number of inquiries including:

• Impurity profiles

• Composition (e.g., composite beta-lactam/beta-lactamase inhibitor antibiotics)

• Metabolic products in bodily fluids

• Reaction monitoring/kinetic profiling at-line or on-line

• Benchtop nuclear magnetic resonance spectroscopy for pharmacopeial assays of over-the-counter medicines: Using quantum mechanics to reduce time requirements and lower accessibility barriers for industrial quality control (2024) Joint USP-Nanalysis App Note

• Quality Control Assays of a Common Food Additive: Monosodium Glutamate (2024)

• Assays of Diethyl Sebacate via 1H Benchtop qNMR: an Alternative Approach to
  Quality Control (2024)

• Simultaneous Degree of Polymerization and Purity Assays of Octoxynol 9 Using 1H Benchtop NMR Spectroscopy (2024)

• Acetyltributyl Citrate and Tributyl Citrate: Plasticizer Assays for Quality Control Using Benchtop NMR Spectroscopy (2024)

• Sodium Formaldehyde Sulfoxylate: Bleaching Agent Assays via 1H Benchtop NMR Spectroscopy (2023)

• Assays of Sodium Succinate via 1H Benchtop qNMR: a Direct and Efficient Approach (2023)

• Paraben Assays: An Efficient and Greener Alternative to HPLC(2023)

• Degree of Deacetylation Determination in Chitosan According to USP-NF Monograph Method Using 1H Benchtop NMR (2022)

• Average Polymer Length Determination for Polyoxyl 10 Oleyl Ether (Oleth-10) According to USP-NF Monograph Method Using 1H Benchtop NMR (2022)

• Average Polymer Length Determination for Polyoxyl 20 Cetostearyl Ether (Ceteareth-20) According to USP-NF Monograph Method Using 1H Benchtop NMR (2022)

• Molar Substitution Determination in Hydroxypropyl Betadex According to USP-NF/Ph. Eur. (1804) Monograph Method Using 1H Benchtop NMR (2022)

• White paper download - Benchtop NMR for pharmacopeial assays Democratization of Nuclear Magnetic Resonance via Benchtop Spectrometry: Increasing Accessibility to Standardized Testing Methods in Quality Control Environment

• Quantification of Amyl Nitrites in Inhalant Mixtures Using Quantitative NMR (2021)

• Assay of an Active Pharmaceutical Ingredient (API) in Formulated Tablets via Benchtop qNMR (2020)

• Amine (R) and (S) Chirality Analyzer: Chemosensors & 19F Benchtop NMR Spectroscopy (2017)

• Automatic, High-Throughput Data Processing: Illustrated through NSAIDs (2016)

• Quantification of Composite beta-lactam/beta-lactamase Antibiotics (2015)

If you’re interested in software packages that ease incorporation of your benchtop NMR, please inquire about:

• Installation Qualification/Operational Qualification (IQ/OQ) software modules

• Advanced User interface for optional application programmatic interface to write own pulse programs or control instrument remotely

• Developments of CFR 21 Part 11 Compliance.

For more information about incorporating benchtop NMR into your daily workflow, please inquire for free sample submission, optional automation, building a database and other tools.