Welcome to Nanalysis’ benchtop NMR Blog

We love benchtop NMR! In this blog section, you will find all things benchtop NMR. Please contact us if you would like to discuss about your project.

Industry Matt LeClerc Industry Matt LeClerc

Benchtop NMR spectroscopy for pharmacopeial assays of over-the-counter medicines

This blog post introduces some of the results we obtained in the collaborative publication of our white paper with the United States Pharmacopeia. It discusses the use of benchtop NMR spectroscopy for the analysis of over-the-counter medicines, and showcases how quantum mechanics can help reduce time requirements and lower accessibility barriers for industrial quality control.

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Educational Susie Riegel Educational Susie Riegel

Why 100 MHz Benchtop NMR?

While low-field NMR has extremely favourable accessibility and affordable characteristics, the most common question that we get asked about our family of benchtop NMR spectrometers is with respect to any trade-offs that come from moving to lower-field.

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Educational Alexander Köring Educational Alexander Köring

How does the lock work?

Magnets used to manufacture low-field and high-field NMR spectrometers are not perfect and the magnetic field that they generate is prone to drift for a variety of reasons. However, during an NMR experiment it is important to keep the magnetic field as stable as possible to prevent the signals from drifting. This is taken care of by the lock system.

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Educational Thais Barbosa Educational Thais Barbosa

Origin of Chemical Shifts

It is common to mention the frequency of an NMR instrument instead of its field. When someone says: I have in my laboratory a 100 MHz instrument, it means that a spectrometer where the protons precess with a frequency of 100 MHz (Lamour frequency) is available in the lab…

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Educational Susie Riegel Educational Susie Riegel

DEPT: A tool for 13C peak assignments

Distortionless Enhancement by Polarization Transfer (DEPT) is a double resonance pulse program that transfers polarization from an excited nucleus to another – most commonly 1H → 13C. This results in a sensitivity enhancement relative to the standard decoupled 1D carbon spectra (13C), which benefits only from the small Nuclear Overhauser Effect (NOE) enhancements.

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