qNMR

While often overlooked, the inherently quantitative nature of NMR Spectroscopy is gaining increasing recognition in the field as a greener alternative to quantify a number of key parameters. Explore the latest in quantitative benchtop NMR assay development.

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NEW Software - qNMR module
A new automated, easy-to-use software module to allow you to create and edit method to automate routine qNMR assays and allow technicians to collect data effortlessly.

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NMR acquisition parameters and qNMR
Beyond structural elucidation, introduction to qNMR – Part I
Beyond Structure Elucidation - Introduction to qNMR Part II – Calibrants
Beyond Structural Elucidation - Introduction to qNMR Part III - Relaxation Delays
Cheat codes for 13C qNMR
Quantifying Lithium Brines with Lithium-7 Benchtop NMR Spectroscopy

Peer-Reviewed Published Papers:

Lithium-7 qNMR as a method to quantify lithium content in brines using benchtop NMR
3,4-Methylenedioxymethamphetamine quantification via benchtop 1H qNMR spectroscopy: Method validation and its application to ecstasy tablets collected at music festivals
Analysis of lignins using 31P benchtop NMR spectroscopy: quantitative assessment of substructures and comparison to high-field NMR
Benchtop nuclear magnetic resonance performance evaluation according to ASTM E691–22 on a population of instruments: Molar substitution determination in hydroxypropyl betadex as a case study for use in quality control environments

Undergraduate Sample Experiments:

Quantification of Pseudoephedrine in OTC Medications
Quantification of Active Pharmaceutical Ingredients Present in Over-the-Counter Medication via 1H NMR Spectroscopy

USP Application Notes:

Assays of Diethyl Sebacate via 1H Benchtop qNMR: an Alternative Approach to
Quality Control (2024)
Simultaneous Degree of Polymerization and Purity Assays of Octoxynol 9 Using 1H Benchtop NMR Spectroscopy (2024)
Acetyltributyl Citrate and Tributyl Citrate: Plasticizer Assays for Quality Control Using Benchtop NMR Spectroscopy (2024)
Sodium Formaldehyde Sulfoxylate: Bleaching Agent Assays via 1H Benchtop NMR Spectroscopy (2023)
Assays of Sodium Succinate via 1H Benchtop qNMR: a Direct and Efficient Approach (2023)
Paraben Assays: An Efficient and Greener Alternative to HPLC (2023)
Degree of Deacetylation Determination in Chitosan According to USP-NF Monograph Method Using 1H Benchtop NMR (2022)
Average Polymer Length Determination for Polyoxyl 10 Oleyl Ether (Oleth-10) According to USP-NF Monograph Method Using 1H Benchtop NMR (2022)
Average Polymer Length Determination for Polyoxyl 20 Cetostearyl Ether (Ceteareth-20) According to USP-NF Monograph Method Using 1H Benchtop NMR (2022)
Molar Substitution Determination in Hydroxypropyl Betadex According to USP-NF/Ph. Eur. (1804) Monograph Method Using 1H Benchtop NMR (2022)