Proton and carbon NMR analyses are routinely used in organic laboratories. In proton, 1H-1H coupling pattern is well exploited, and 1H-13C couplings as referred to as the carbon satellites. However, when acquiring carbon data, proton decoupling is applied most of the time and consequently it is not common to evaluate 1H-13C couplings in routine carbon analysis. This blog discusses the 1H-13C coupling in tert-butanol through 1D and 2D data, highlighting the key info. Read more.

2D NMR experiments provide chemists with evidence to clarify and confirm resonance assignment.  Nowadays every organic chemist uses these experiments called COSY, HMBC and HSQC as routine analytics. Basically, with 2D experiments you correlate some kind of information between two 1D spectra. If we correlate two 1D spectra of the same nucleus we are dealing with homonuclear 2D NMR experiments. The most famous representative of this group is the COSY experiment (find theory here and application here).