Welcome to Nanalysis’ benchtop NMR Blog

We love benchtop NMR! In this blog section, you will find all things benchtop NMR. Please contact us if you would like to discuss about your project.

Educational Godfrey Wills Educational Godfrey Wills

Using NMR to observe the restricted rotation in amide bonds

NMR is a great tool for the analysis of molecular properties such as the amide bond, which has a restricted rotation around the C–N bond. In Biochemistry, the amide bond is referred to as the peptide bond. This bond is formed by the union of a carboxyl group of one amino acid with the amino group of another amino acid. Read more.

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Educational Eva Lam Educational Eva Lam

DEPT: A tool for 13C peak assignments

Distortionless Enhancement by Polarization Transfer (DEPT) is a double resonance pulse program that transfers polarization from an excited nucleus to another – most commonly 1H → 13C. This results in a sensitivity enhancement relative to the standard decoupled 1D carbon spectra (13C), which benefits only from the small Nuclear Overhauser Effect (NOE) enhancements.

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Industry Jonathan Ma Industry Jonathan Ma

Valentine’s? More like Valen-time to get some new lipstick!

With Valentine’s Day quickly approaching, some of you may be planning for that special date you have planned. Maybe you’ll go for the glossy look, maybe the matte; should I go for a light tone, or something that pops? Well, before you even think about that, check those expiration date! With the nature of lipsticks being opened and closed, they are highly susceptible to oxidation, so read more to find out!

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Educational Alexander Maier Educational Alexander Maier

Labile Protons and J-Coupling

Have you ever questioned why hydroxyl groups/alcohol signals appear as singlet in the 1H NMR spectrum? Shouldn’t they also couple with neighboring hydrogen atoms and show the corresponding splitting pattern? Yes…no…why? Don’t worry! We’ll get to the bottom of it and discuss how exchange rates, concentrations, and the presence of water affect the NMR spectra of ethanol in CDCl3. Benchtop NMR solves so many questions – feel free to reach out to us to make sure yours can answered too.

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Educational Matt LeClerc Educational Matt LeClerc

Spin-Spin Coupling – Beyond Multiplicity

Nuclear magnetic resonance (NMR) is a critical tool for scientists undertaking structural elucidation or quantification of species in mixtures. Along with single crystal X-ray diffraction (SCXRD), no other technique provides as much information about a molecule’s conformation as NMR. This approach provides information about molecules in solution. Benchtop NMR 1-855-NMREADY (667-3239) toll-free in the US and Canada

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Educational Thais Barbosa Educational Thais Barbosa

Why does NMR have an inherently low sensitivity?

It is well known that NMR analysis requires a higher concentration of analyte than any other spectroscopic method. For example, UV-Vis requires an analyte concentration range of only nM to µM, while NMR typically requires the analyte to be in the mM range (>1000 times more concentrated!). In this blog, we will demonstrate why NMR is considerably less sensitive than UV-Vis. We have chosen UV-Vis for this comparison as it is widely recognized as one of the most sensitive spectroscopic techniques.

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Educational Jonathan Ma Educational Jonathan Ma

SANTA DOESN’T JUST LIKE ANY COOKIE! Read More to Find Out How to Get on Santa's Good Side

This year, to bring out that Christmas spirit inside of everyone, I would like to talk about Santa Claus. Now, I know there are a plethora of Christmas treats out there that you will be making, but for the big man flying through the skies, there is one treat that stands head and shoulders above all else. I’m talking, of course, about cookies. However, with the never-ending list of cookies the big question becomes: which one are you making for Santa? With this blog, I might be able to provide you with a little bit of guidance.

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Industry Paul Hui Industry Paul Hui

Quantifying Lithium Brines with Lithium-7 Benchtop NMR Spectroscopy

The use of lithium around the world has increased drastically in recent years due to the superior performance of lithium-ion batteries. These batteries are heavily used in everyday life as they are present in our phones, computers, watches, vehicles, and many more devices. However, before these batteries can be produced, we need to procure lithium from somewhere.

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