‘The spectra were analyzed according to first order’. Does this sound familiar to you? Most of the supporting information documents out there contain this sentence. You find yourself asking ‘why does nobody care about second order effects?’, then check out this high-order blog entry on the topic.

Are you familiar with the apodization tool in Mnova? Apodization (also referred to as Weighting or Windowing) literally translates to ‘cutting off the feet’ from the original Greek. In this case…

If you’ve ever prepared an NMR sample, you’re familiar with the fact that we almost always use deuterated solvents to dissolve our samples of interest…

While low-field NMR has extremely favourable accessibility and affordable characteristics, the most common question that we get asked about our family of benchtop NMR spectrometers is with respect to any trade-offs that come from moving to lower-field.

Sugar substitutes are gaining more and more relevance due to the health problems associated with the consumption of high amounts of sugar...I thought it would be interesting to take a few of those substitutes and acquire their proton NMR spectrum in our benchtop NMR.

Chirality has a huge impact on the chemistry of a molecule. Due to potentially different physiological effects, pharmaceutical compounds are often used as enantiomerically pure compounds. One enantiomer can act as a healing agent, the other might be toxic to humans. Crazy, right?

The media is bombarding us daily with two messages on opposite sides of the coin. One message displays record-high infection rates due to COVID-19, while the other focuses on the release of messenger RNA (mRNA) vaccines initially by Pfizer-BioNTech, followed by Moderna. With so many drastic changes…

In the average case one can simply dissolve an analyte in an appropriate deuterated solvent and acquire a simple 1D spectrum to obtain all the required structural information. However, sometimes doing so may not provide you with all of the information you need!

The communication of nuclear spins is not limited to nuclei of the same ‘type’. Atoms that have a nuclear spin (i.e., I ≠ 0) are affected by the same phenomena that cause protons to communicate and ultimately split each other’s NMR signal.