Welcome to Nanalysis’ benchtop NMR Blog

We love benchtop NMR! In this blog section, you will find all things benchtop NMR. Please contact us if you would like to discuss about your project.

Academic Juan Araneda Academic Juan Araneda

Life is sweet….maybe too sweet!

Sugar substitutes are gaining more and more relevance due to the health problems associated with the consumption of high amounts of sugar...I thought it would be interesting to take a few of those substitutes and acquire their proton NMR spectrum in our benchtop NMR.

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Academic Terry Chu Academic Terry Chu

Monitoring Suzuki Coupling Reactions with Benchtop NMR

2D NMR experiments provide chemists with evidence to clarify and confirm resonance assignment.  Nowadays every organic chemist uses these experiments called COSY, HMBC and HSQC as routine analytics. Basically, with 2D experiments you correlate some kind of information between two 1D spectra. If we correlate two 1D spectra of the same nucleus we are dealing with homonuclear 2D NMR experiments. The most famous representative of this group is the COSY experiment (find theory here and application here).

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Academic Juan Araneda Academic Juan Araneda

Nucleophilic Substitution Reactions and Benchtop NMR

Nucleophilic substitution reactions are frequently performed as an experiment in undergraduate organic chemistry courses. Reactions taking place at saturated carbons are mainly classified as SN1 or SN2, where S stands for substitution, N for nucleophilic, and the number indicates the molecularity of the reaction (1 for a unimolecular process, 2 for a bimolecular process). In the SN2 reaction the attack of the nucleophile and elimination of the leaving group occur simultaneously in a concerted process and its rate is proportional to the concentration of both the alkyl halide and the nucleophile.

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Academic Juan Araneda Academic Juan Araneda

Life is sweet….maybe too sweet!

Sugar substitutes are gaining more and more relevance due to the health problems associated with the consumption of high amounts of sugar...I thought it would be interesting to take a few of those substitutes and acquire their proton NMR spectrum in our benchtop NMR.

Read More
Academic Susie Riegel Academic Susie Riegel

Assessment of Stereoselectivity of Wittig Reaction with 60 MHz 1H NMR Spectroscopy

The Wittig reaction is a high-yielding, versatile synthetic procedure used to construct carbon-carbon double bonds. Unlike other sp2 bond forming reactions this can be used to provide convenient access to a cis– stereochemistry. At the time the reaction was discovered by Georg Wittig, this cis– confirmation was not reliably afforded by other synthetic means. To …

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