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Educational Alexander Maier Educational Alexander Maier

β-Diketone (Beta-diketone) tautomerization ratio determined via 60 MHz benchtop NMR

Tautomers are constitutional isomers that interconvert into each other by an exchange reaction, most commonly a proton transfer. Such two isomers can for example be a ketone and an enol. Keto-enol tautomerism (KET) becomes possible when there are hydrogen atoms adjacent to a carbonyl group (these hydrogen atoms are called α hydrogens). This tautomerism is depicted in Scheme 1 and is also discussed…

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Educational Alexander Maier Educational Alexander Maier

β-Diketone (Beta-diketone) tautomerization ratio determined via 60 MHz benchtop NMR

Tautomers are constitutional isomers that interconvert into each other by an exchange reaction, most commonly a proton transfer. Such two isomers can for example be a ketone and an enol. Keto-enol tautomerism (KET) becomes possible when there are hydrogen atoms adjacent to a carbonyl group (these hydrogen atoms are called α hydrogens). This tautomerism is depicted in Scheme 1 and is also discussed…

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Academic Juan Araneda Academic Juan Araneda

Life is sweet….maybe too sweet!

Sugar substitutes are gaining more and more relevance due to the health problems associated with the consumption of high amounts of sugar...I thought it would be interesting to take a few of those substitutes and acquire their proton NMR spectrum in our benchtop NMR.

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Academic Juan Araneda Academic Juan Araneda

Electronegativity and Chemical Shift

Electronegativity is a concept that we have to study and understand early in our science or engineering degrees. In chemistry this concept stays with us and we commonly invoke it in order to explain multiple phenomena what we observe or study…and of course, NMR is not the exception! Benchtop NMR 1-855-NMREADY (667-3239) toll-free in the US and Canada

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Academic Terry Chu Academic Terry Chu

Evans Method with NMReady-60 for understanding 1H NMR of Paramagnetic Compounds

Due to the presence of unpaired d electrons in their metal ions, many transition metal complexes are paramagnetic. The unpaired electrons have a magnetic dipole moment due to their spin and act like tiny magnets, resulting in a small net attraction to an externally applied magnetic field. Unsurprisingly, the presence of paramagnetic ions has significant effects on both the chemical shift and lineshape of the 1H NMR spectrum of transition metal complexes, with the chemical shift range being much wider along with broadening of the signals.

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Academic Juan Araneda Academic Juan Araneda

Life is sweet….maybe too sweet!

Sugar substitutes are gaining more and more relevance due to the health problems associated with the consumption of high amounts of sugar...I thought it would be interesting to take a few of those substitutes and acquire their proton NMR spectrum in our benchtop NMR.

Read More