We are thrilled to introduce Nanalysis’ latest value-added software module, qNMR.
Quantitative NMR (more commonly referred to as qNMR) is an outstanding tool that’s getting more attention because it is a great way to accurately quantify one or multiple analytes, the sample preparation is easy, the experiment time is short and you can use any substance of known purity as internal calibrants unlike chromatographic methods where reference material of the same identity as the analyte are required. Furthermore, you’re facing much lower running costs due to less solvent being used and lower disposal volumes compared to HPLC assays. We have written multiple application notes, peer-reviewed publications, and blog posts to explain qNMR in detail and to show its utility in multiple industrial settings that we encourage you to review.
To help qNMR find its way quickly into QA/QC environments, we have automated the analysis to remove the expertise barrier to this powerful technique. Additionally, user permission levels guarantee integration into GMP workflows with administrators having full access for creating and modifying methods by defining the acquisition parameters, the integral ranges, or other settings, while technicians cannot do something wrong in their restricted area.
To give an example let’s create and run a quantification method for Ibuprofen purity determination for outgoing goods. First, the administrator’s view on developing a new method (Figure 1) by defining the appropriate acquisition parameters, and inserting some specifics, mainly regarding the calibrant and analyte nature, then saving the method with a title that allows technicians to easily identify it.